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Rhosin hydrochloride
CAS No. 1281870-42-5
Rhosin hydrochloride ( —— )
Catalog No. M23446 CAS No. 1281870-42-5
Rhosin hydrochloride is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0.4 uM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 206 | In Stock |
|
| 5MG | 312 | In Stock |
|
| 10MG | 447 | In Stock |
|
| 25MG | 714 | In Stock |
|
| 50MG | 972 | In Stock |
|
| 100MG | 1305 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRhosin hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionRhosin hydrochloride is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0.4 uM).
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DescriptionRhosin hydrochloride is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0.4 uM). Rhosin hydrochloride does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin hydrochloride causes cell apoptosis.
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Synonyms——
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PathwayApoptosis
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TargetApoptosis
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RecptorApoptosis;RhoA
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Research Area——
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Indication——
Chemical Information
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CAS Number1281870-42-5
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Formula Weight394.9
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Molecular FormulaC20H19ClN6O
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Purity>98% (HPLC)
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SolubilityDMSO:100 mg/mL (253.25 mM; Need ultrasonic)
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SMILESO=C(N/N=C/C1=CC=C2N=CC=NC2=C1)[C@H](N)CC3=CNC4=C3C=CC=C4.Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Shang X, et al. Rational design of small molecule inhibitors targeting RhoA subfamily Rho GTPases. Chem Biol. 2012 Jun 22;19(6):699-710.
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